Coronavirus Epidemic Update 26: Treatment Updates, Stock Markets, Germany & San Francisco, Pandemic?

Coronavirus Epidemic Update 26: Treatment Updates, Stock Markets, Germany & San Francisco, Pandemic?

welcome to another Tsarskoe v2 COVID-19
updates we got numbers we got germany san francisco stocks delta corona virus
vaccine treatment in the US and pandemic and that is with a question mark so
let’s get right to the numbers if we go to the world ometer website if we look
at the number of active cases you can see that 82 percent of those are in mild
condition whereas 18 percent are serious or critical remember these are patients
that got tested because they had symptoms and i imagine that there’s far
more people out there than we know that had corona virus were asymptomatic and
didn’t even know if we look at the close cases this is something that we’re
following people who have gone through the corona virus and come out the other
side or have not come out the other side we’re seeing that about 92 percent of
them have recovered on our discharge in our home and eight percent have died if
we look at the graph of that we can see here that this has not yet reached the
asymptote according to these numbers if you believe them death rate is eight
point four two percent and dropping for those of you who don’t trust the numbers
coming out of China this is an interesting graph here where we look at
the total cases outside of China and you can see that those are going up and
we’re sort of in the epidemic phase especially in South Korea and in Italy
if we look at daily cases excluding mainland China we’ve got here on the
25th of February the highest number to date but please remember that those
cases that are outside of China are just a sliver of the total cases that are
reported by mainland China of course if those numbers in China are far greater
than what they’re reporting then the sliver is even smaller than it is
represented here again back on the main page at the bottom below all of the
countries specific data we have the latest updates during one new death in
Japan three new cases in Thailand and they say that we are entering a full war
with kovat 19 and one new death in South Korea a 73
year-old male if we go back to February 25th
there are 406 new cases and 52 new deaths occurring in China on February
25th as reported by the National Health Commission of China also one new death
in South Korea a female patient who died of acute respiratory failure after being
a minute up to just two days being in the hospital one new death on the
diamond princess this is a person in their 80s two new cases in Italy 60 new
cases in South Korea which is a sharp decline in new cases compared to
yesterday’s 161 new cases so I’ll have to see how that pans out on CNBC they
are reporting as part of their update that there are new coronavirus cases in
Germany this is a 25 year old man living in southern German state of Baden
württemberg and he had a return visit from Italy
he had flu-like symptoms and he’s gonna be treated in isolation and people who
have been in contact with them are going to be put in isolation also see here
that San Francisco has declared a local emergency and they have a total caseload
of zero but they are trying to take a proactive action kind of an interesting
thing of course the big news of the day is somebody at the CDC which we’ll talk
about said that it’s not a matter of if but a matter of when Cova 19 comes to
the United States in full force and of course that caused the markets to lose
up to 800 points also we see here that Delta scraps cancellation fees for
Italian flights because of that outbreak big news here is that US health
officials say that human trials on coronavirus vaccine is going to start in
six weeks and we talked about this on the last update and how it is so
different than the previous examples of vaccines that we’ve had and that’s
because instead of injecting you with a protein that your immune system makes
antibodies against what they’re going to be doing is injecting you with the
instructions that is the RNA into your cell so that the antigen presenting
cells that normally present these antigens to your immune system will make
the protein on its surface and then present it to your immune
system to make the antibodies against it this allows you to make manipulations as
the virus apparently mutates it also cuts down on
production time it allows you to get a vaccine out during an epidemic as
opposed to after the epidemic has passed and a lot of people have suffered from
this and it also allows you to scale and reach millions and millions of people
with this type of vaccine and we talked about that yesterday we got more
information about that today here’s a really interesting article this is from
Harvard University and believe it or not this was published in May of 2015 that’s
five years ago that they were looking at this type of technology and we’ll leave
a link to this website in the description below goes through a lot of
interesting things for instance a lot of questions yesterday regarding how do you
get this RNA into the cells well it talks about what RNA does and I would
recommend you watch our molecular biology primer which will put the link
to to bone up if you will on exactly how does the cellular
structure work because that’s going to become really important for you to
understand if you want understand how these vaccines work so that talks about
that here it says in the living cell of the organism DNA is the molecule that
contains the genetic information of that organism it’s composed of a series of
four building blocks which we talk about that gets copied into a structure called
RNA which carries that information into the rest of the cell that’s the cytosol
or the cytoplasm and it’s there that this RNA genetic information is
translated into proteins so you can see here what happens is you get injected
this is the RNA that they have figured out it goes into your special type of
cells called antigen presenting cells these are typically the cells that go
around looking for things that shouldn’t be there eating them up and presenting
the antigens usually proteins to your immune cells that’s how a normal vaccine
works well here these little code instructions will go into the antigen
presenting cell and the cell itself will make a portion of the viral protein the
portion that they feel is the best to make antibodies against they will make
that protein inside of their own cells and present it which will stimulate the
immune response and RNA is injected into the body this
RNA encodes the information to produce the antigen which is a protein from a
pathogen that will stimulate the immune system inside the cells the RNA is used
to synthesize the antigen which is exposed to the cell surface this is the
new part here then a subset of immune system cells recognize the antigen and
trigger an immune response so it’s quite interesting you can see here that once
you have the real pathogen that comes in you already have the immune system built
up and you can get a rapid response or a strong response and I will put a couple
of other links of some videos below that describe this kind of technology if you
want more information on that we’re gonna talk about that in subsequent
lectures the next thing I want to talk to you about is this fortunate article
about the first u.s. trial for a corona virus treatment that is started and this
is an interesting situation because of course the question is if we’re gonna do
this in United States who are we going to do it with and this is not a vaccine
this is the treatment and it’s using this medication that we’ve talked about
before called REM des aver now Ramez aver is a antiviral but the way it works
is it is a nucleotide analog that basically prevents and truncates or
stops the ability of RNA to reproduce and make these long RNA strings and
we’ll talk a little bit more about that mechanism in our course on what is a
corona virus and how does it infect the cell and we’re still working on that but
we should be able to have that out shortly the NIH confirmed on Tuesday
that the first u.s. clinical trial for a corona virus treatment has launched at
the University of Nebraska so this is a gold standard study where they are going
to give patients placebo or the real thing and the reason why they’re doing
this is because they don’t know if this medication works but they’re certainly
gonna try to find out and they’re gonna use patients that have already been
infected with kovat 19 that have come back from the diamond princess or have
been quarantined and found to have the corona virus if they develop symptoms so
again who are these patients the first u.s. patient to enroll in the trial is
according to the NIH an American who volunteered for the study the individual
was one of thousands of people quarantined on the
princess cruise ship in Japan before being repatriated to the United States
which all brings us back to the last item and that’s this idea about pandemic
pan of course meaning everywhere ademma keening a situation or infection so the
common cold is a pandemic the flu virus is a pandemic a pandemic simply
describes how broad and far-reaching is this infection what are the US health
officials say based on this news report we have an shoots at the principal
deputy director of the Centers for Disease Control prevention told
reporters at a news briefing quote it’s not so much a question of if this will
happen anymore but rather more question of when this will happen and how many
people in this country will become infected and how many of those will
develop a severe or more complicated disease Health and Human Services
Secretary Alex as are added we can’t hermetically seal off the
United States and so a lot of these people that are being repatriated have
these viruses they’re keeping them in quarantine and we will see how this goes
there is hope of course that we can stave this off and that somehow if
there’s increasing temperatures in spring and summer that perhaps this
might depress the growth of the corona virus there are some examples where this
could be true we have some data to show that this might be true we also have
data that this might not be true right because we have places like Singapore
and warmer countries where there is still a growth of the corona virus so
getting back to our agenda the big story currently is what they’re doing here
with the vaccine with the RNA and what they’re doing with the treatment with
the randomized controlled trial that’s big news and then of course this
pandemic is not going to change what we do in terms of the virus it’s simply
going to change the perception the perception the virus can sometimes be
more dangerous than the virus itself it is best to do what you can do on a
rational basis to improve your chances of not getting the corona virus but if
you do surviving it

100 thoughts on “Coronavirus Epidemic Update 26: Treatment Updates, Stock Markets, Germany & San Francisco, Pandemic?

  1. Please subscribe to receive notifications about new MedCram videos.
    Visit us at for clear explanations of over 60 medical topics.
    All links referenced in this video are in the video description.
    Quick links to our other videos on Coronavirus (COVID-19):
    – Coronavirus Epidemic Update 25: Vaccine Developments, Italy's Response, and Mortality Rate Trends:
    – Coronavirus Epidemic Update 24: Infections in Italy, Transmissibility, COVID-19 Symptoms:
    – Coronavirus Epidemic Update 23: Infections in Kids & Pregnancy, South Korea, Spillover From Bats:
    – Coronavirus Epidemic Update 22: Spread Without Symptoms, Cruise Quarantine, Asymptomatic Testing:
    – Coronavirus Epidemic Update 21: Antibodies, Case Fatality, Clinical Recommendations, 2nd Infections?:
    – Coronavirus Epidemic Update 20: Misinformation Spread, Infection Severity, Cruise Ship, Origins:
    – Coronavirus Epidemic Update 19: Treatment and Medication Clinical Trials:
    – Coronavirus Epidemic Update 18: Cellphone Tracking, Increase in Hospitalizations, More Sleep Tips:
    – Coronavirus Epidemic Update 17: Spike in Confirmed Cases, Fighting Infections with Sleep (COVID-19):
    – Coronavirus Epidemic Update 16: Strengthening Your Immune Response to Viral Infections (COVID-19):
    – Coronavirus Epidemic Update 15: Underreporting, Prevention, 24 Day Incubation? (COVID19):
    – Coronavirus Epidemic Update 14: Hospital spread of infection, WHO allowed in China, N-95 masks:
    – Coronavirus Epidemic Update 13: Li Wenliang, nCoV vs Influenza, Dip in Daily Cases, Spread to Canada:
    – Coronavirus Epidemic Update 12: Unsupported Theories, Pneumonia, ACE2 & nCoV:
    – Coronavirus Epidemic Update 11: Antiviral Drugs, Treatment Trials for nCoV (Remdesivir, Chloroquine):
    – Coronavirus Epidemic Update 10: New Studies, Transmission, Spread from Wuhan, Prevention (2019-nCoV):
    – Coronavirus Epidemic Update 9: Fecal-Oral Transmission, Recovery vs Death Rate:
    – Coronavirus Outbreak Update 8: Travel Ban, Spread Outside of China, Quarantine, & MRSA:
    – Coronavirus Epidemic Update 7: Global Health Emergency Declared, Viral Shedding:
    – Coronavirus Outbreak Update 6: Asymptomatic Transmission & Incubation Period:
    – Coronavirus Update 5: Mortality Rate vs SARS / Influenza:
    – How Coronavirus Kills: Acute Respiratory Distress Syndrome (ARDS) & Treatment:
    – Coronavirus Update 3: Spread, Quarantine, Projections, & Vaccine:
    – Coronavirus Symptoms, Diagnosis, Treatment:
    – Coronavirus Outbreak – Transmission & Updates:

  2. Numbers mean nothing
    Can’t trust it
    Epidemic or pandemic?
    What’s the real difference?
    National health commission or who all the same bs

  3. i was wondering..if there is no cures for the common cold..or sars..or mers…how could they make one for this virus?? its in the same family how can they make a vaccine?? dont you have to shed a virus..and take anti biotics for bacterias?? they wont work on virus–right?? i have i am concerned on what exactly to do or take or have on hand to expel and lung mucus..they say thats whats killing people..they drown on the lung fluids…and how does a person get more oxygen into the bloodstream..thank you…wondering if hiv/malaria drugs would be of help..combinations of??

  4. CA has it, unknown origins…really? We all know the origins. Should have locked down earlier. Hopefully it doesn't get worse in the US. Then it's triage. Everyone take care and stay healthy.

  5. I thank you sincerely for keeping us updated, I have been referring friends and family to your videos. I really appreciate how dedicated you are to this and keeping us informed. Excellent videos.

  6. Vaccine = First phase test, a few patients, wait 6 months watching for secondary effects. Second phase, thousands of patients, wait 6 months watching for secondary effects. Third phase, more test, research and development, 6 months. So, the vaccines will be ready in 18 months minimal. I dont see you explaining that, are you prioritizing your savings than sharing factual information? Not cool.

  7. Thank you for the daily updates!!! I’m a registered nurse and would love to keep my family, friends, patients, and coworkers updated.

  8. Dr thank you for these videos… May God Bless you and all medical people working to stop this virus and all the angels of mercy who are working for the good of humanity

  9. Dr. Anthony Fauci, the National Institutes of Health's infectious disease chief, told CNN on Wednesday that the first clinical trials for a possible coronavirus vaccine could begin in one to two months. He said a vaccine is a year to a year-and-a-half away

  10. Don’t care anymore.
    I tried warning family, friends and colleagues weeks ago… they didn’t want to know.
    F*ck ‘em all.
    I’m done. I’m out.
    Gonna sit back and watch the world burn.
    Humanity is finished. We blew it.
    Hubris, ignorance and wanton stupidity.
    It’s time for another species to rise up.


  12. But isn't it true that even if a vaccine is ready for human trials in 6 weeks it could still take months for it to be widely and safely used? Kinda important to mention this I guess.

  13. I thought the Enlightenment was supposed to improve everything, you know, reason over superstition, science over religion, talking over fighting, yada-yada-yada. But then … Why is everyday the Apocalypse five hundred years after the Enlightenment began? I think we need a new ethical/mythological system to deal with our current world. I do not think Enlightenment is working anymore.

  14. An unknown origin case to a person who has not traveled in Northern California was reported today, sounds interesting. My opinion is that the virus is air born and unavoidable at this point just hope your immune system is strong enough to not only fight it but adapt to the virus

  15. Which warmer countries have seen a growth? You can't count Middle East as they are imported from cold Iran. Japan and South Korea are cold. Singapore has 93 cases mostly imported. South East Asia has 52 active cases in a population of 650 million. Please someone do the maths…

  16. If you don’t live in an area plagued by the coronavirus should you still be worried? Because I don’t believe we should start preparing bunkers and canned food but clearly some people are so should we? Finally, how should we go about traveling by plane? I know it’s highly risky to travel just as has been shown with the cruise, but how dangerous is it to travel to less infected areas? It’s be great if some could answer some of the questions thanks!

  17. Stock market in the US has dropped twice by the mere mention of a possibility of a pandemic. What's gunna happen if it is declared to be a full pandemic emergency?

    ..idk but I'm stocking up on emergency supplies just in case

  18. Nice analysis covering all aspects of Covid 19 , let me share with you information about Covid 19 in Pakistan where 2 people tested positive of CoronaVirus both of whom travelled recently to Iran.

  19. Just getting over a pretty bad cold/fever with a bad sore throat and cough. Haven’t had a sickness like this for awhile and it has affected a lot of ppl I know around my area. Going out on a limb, but we aren’t even really testing for it. I didn’t go to the doctors but my family did and they simply stated it was a very contagious cold/fever that targeted the respiratory system for 7-10 days recovery time. Did they have legit testing kits for the virus at the clinic? I highly doubt it, so I wouldn’t be surprised if it is already in full scale spread already.

  20. Is it possible that Convid-19 is a bio weapon given the constant changes the perceived incubation period of the virus from 32 days to 30 days to 28 days and now 2 week incubation period is being reported?

  21. For those of you worried about the safety of the RNA vaccine, I will make one educated guess:

    1. You will get just enough RNA so a limited number of cells make the protein that will trigger the immune response. The RNA won't replicate inside your body, so the mechanism is auto-limited. The cells could replicate but maybe the RNA have instructions to induce apoptosis or to prevent cell replication, thus limiting the whole process.

    Just my two cents.

    Thank you so much Dr Seheult for your daily report which is a guidance for many of us.

  22. How this coronavirus will affect people with chronic bronchitis? Is it possible that this pre-existing disease can cause a very serious case even death?

  23. Dr Scheult can you please comment on why Italy is said not to have found Patient 0 and if so, how the virus started to spread in Italy? Thanks

  24. In Peru, there is lady traveler that came from Bolivia with coronavirus type symptoms. Apparently she had contact with Chinese residents. This is hitting South America :s

  25. how reliable is this new type of of vaccine compared to the traditional type? and what are the potential side effecting from this?
    thank you for your updates and info. i am not a doctor or med student but your videos are very useful and helpful

  26. The government claims to know how many are wandering arround with mild cases unaware of their contagion capability. Pres. Trump only talks about the positive and is not transparent about the big negatives in the virus progression and huge economic problems ahead. He's just trying to make it to the election at the cost to the public. I hope he makes it despite the weaponized virus released to stop him by an economic crash and world depression. And, there are those that would stave off prosecution for huge crimes against the people of the nations.

  27. Sometimes, i think that some infected chinese ppl fled their country to seek medication from other wealthy countries. That’s why it infects other countries too. It’s just my thoughts.

  28. Wait wtf. Human trials in 6 weeks!?!? Injecting RNA? So directly inducing an immune response?
    So.. how do you stop the body from making anti bodies? It just keeps making anti bodies? I don't get it. That sounds like an auto immune disease.
    Edit: Holy crap, that's fascinating, I've never heard of this!

  29. Hello Dr Seheult and fellow Medcrammers. I was wondering why the RNA treatment activates the antibody mediated response if the RNA “infects” the cell. Wouldn’t the cell mediated response be activated instead, resulting in T cell activation and thus T killer lymphocytes killing the cells that have the injected RNA and hence the foreign antigens. Thanks for all your videos, your well organised videos have been amazing over the last month.

  30. Thank you Doctor. Ive been watching since update 1 and you have not been using the fear tactic and giving facts and this puts my mind at ease. Thank you so much. Please continue the updates

  31. Don’t trust the numbers coming out of China, Iran, or the US. US has faulty test kits, is testing very small numbers, and has a lame and obsequious virus czar.

  32. Remdesivir blocks RNA in utero also ⚠ teratogenic
    ⚠ warning as dangerous to an expectant mum as the virus itself…
    First trimester miscarriage or severe birth defects as with Rubella

  33. 9:46: "We can't hermetically seal off the United States." -Azar. Uh, yes you can… and you should. All international travel needs to be halted and grounded, while the CDC gets to work retracing all sources of infection. Naturally, if we had a competent administration, in the midst of a global pandemic… we would have already taken such extraordinary steps. Instead, we'll need to show our leaders the 2011 film, "Contagion," if we expect them to understand and comprehend the seriousness of what's going on.

  34. The key is isolation not quarantine. 100 people quarantined in an army barracks or a warehouse with just one asymptomatic but infected person is a test tube prepared for infection. Remember that the vectors for infection are touch, water droplets and aerosol. Remember that there are cases of asymptomatic persons showing no signs of the disease for up to 28 days. The protocols for quarantine must be speedily and intelligently and completely re-formulated. In Wuhan they have begun locking down the entire population in their apartments and houses. They have no choice. The key is isolation. Watch the videos coming out of Wuhan for the last month. Quarantine has not worked. The evidence in the videos is compelling. To ignore or disregard the evidence is criminal, unscientific and foolish. The key is isolation.

  35. Is it even possible to develop a vaccine for corona? Because you can be infected at least a second time after a successful recovery.

  36. America has never check if the people died from flu like disease are really died from this virus. America has never care about their ordinary people. They only know to smear China and to fool their people.

  37. the test by the USA is not really conclusive given the very few patients, surely this should be done under the wHO. money should not come into it.

  38. It seems the Filipinos are immune to this virus.
    445 Workers onboard the Diamond Princess have returned home to the Philippines and NONE of them have tested positive to the virus. Isn't this AMAZING, or is it just BS. Whatdo you think of this.?

  39. What influences the heavy immune reaction to the virus? Is it more likely that the immune system of someone with a chronic inflammation tends to those reactions?

  40. Iran is either lying or has a 20 percent death rate. It's 2.5 percent or less everywhere else. What's going on with them?

  41. Today is the first time that the news are full of articles about the Virus. But the catch is that to this day nobody is sufficiently informed. And i am not talking about the average Joe. I am talking Government. They don't know that this thing most likely is airbourne. They ignore the fact that it can spread from asymptomatic patients. The consider quarantaining people up to 14 days, which probably isn't sufficient. They even don't know who's to decide anything. The Government does nothing because it supposedly is a matter of state level. The states think the EU is to decide. This will spread like wildfire in Germany. I knew it weeks ago. Oh and for many people this thing still isn't as bad as the flu somehow. This country is run by complete baffoons.

  42. I see absolutely no difference between the "coronavirus" and any other virus. The stats are the same and numbers do not reflect AGE related cases, pre existing conditions, immune system functioning, treatment, conditions or biological condition of those who survived and died. I am certain I had this virus and the signs and symptoms fit to a tee. I am a physical therapist and researched this virus. It was extreme as many of my friends went to the hospital all over the U.S. and were put on ventilators. They could not breath. I am in average health with hypothyroidism, level 3 kidney disease, depression and anxiety and am 64 years old. I train with weights and do MMA for exercise (still fight) and this virus hit me with my guard down while cutting weight for a fight.. quickly. I survived, but I was ready to go to the hospital a few times. Don't tell me this virus is not in American, because it is. Many went down here in Las Vegas. Remember swine flu? Yeah, thing about it.

  43. Doctor can you please do a vlog with the best things we can do to prevent be infected with Corona virus. We already know that one is sleep well and clean the hands and avoid contact with crowds. And more?

  44. WHO-Make it finaly pandemic. Wake up all idiots that they stop to think about money. Last days we had carnaval in Germany… All partying and not thinking about covid19… I Bet with you all prohibiting it would saved lot of lives… With pandemic declaration those could be stoped!
    People use co on sense, prepare, stay safe!

  45. Who can scientifically answer my question: what is the difference in R0 1 and R0 4 – is it 4 times more infectious, or 40? How to tell?

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